Faculty Expert Profile
- Professor of Molecular Microbiology and Immunology
- Co-director of the Johns Hopkins Center of Excellence in Influenza Research and Surveillance
- Director of the Center for Emerging Viruses and Infectious Diseases
- Bloomberg School of Public Health
- Johns Hopkins Vaccine Initiative
Andrew Pekosz is a virologist whose research centers on understanding the interaction of viruses with the respiratory epithelium. He is particularly interested in identifying viral and cellular factors that are important for efficient replication of canine, equine and avian influenza A virus strains to human respiratory epithelial cells.
His research primarily focuses on influenza A virus, but he also investigates a number of emerging viruses that pose increasing threats to humans, including severe, acute respiratory syndrome coronavirus (SARS-CoV), enterovirus-D68 (EV-D68), Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV), and Andes virus, a South American hantavirus responsible for Hanatavirus Pulmonary Syndrome (HPS).
He also pursues a better understanding of how viruses can counteract antiviral innate and adaptive immune responses. By identifying the viral proteins that control the host immune response, he hopes to gain a better understanding of how the virus can establish an infection and identify the key host proteins that play a role in controlling virus replication and the immune response to viral infection.