Faculty Expert Profile
- Associate Professor of Medicine
- Johns Hopkins Medicine
- Lyme Disease Clinical Research Center
John Aucott has more than 15 years of research experience on the crippling effects of Lyme disease and has published studies focusing on characteristics of early Lyme disease differences in males and females with an emphasis on prospects for prevention, diagnosis and treatment.
Aucott and a colleague are engaged in a multi-year longitudinal study of patients diagnosed with early-untreated Lyme disease and matched controls, the Study of Lyme disease Immunology and Clinical Events (or SLICE). This has generated a large and unique repository of clinical data and biological samples from patients with a range of clinical outcomes and collected over several seasons.
Aucott recently published on the immune heterogeneity of patients with Lyme disease using samples from this collection. His goal is to utilize these samples to help identify new biomarkers of Lyme disease that will inform as to disease diagnosis, disease outcome and understand disease pathophysiology. Aucott's clinical research site recruits and enrolls participants with untreated early Lyme disease and erythema migrans for these studies. The Lyme sample biorepository will provide serum samples from this collection for the proposed studies and the clinical study team will as aid in the analysis and interpretation of results.