Biotechnology

Johns Hopkins team takes second in business plan competition with corneal surgery enhancement

Treyetech team wins $15,000 at TCU's Values and Ventures Business Plan Competition

Three students pose with an oversized check for $15,000

Image caption: Treyetech members (from left) Stephanie Cai, Conan Chen, and Kali Barnes represented the team at the Values and Ventures Business Plan Competition at Texas Christian University

A team of eight Johns Hopkins University undergraduate students took second place in the international Values and Ventures Business Plan Competition at Texas Christian University last week for their novel design to help transport and implant tissue during corneal surgery.

The Hopkins team competed against teams from 51 schools from across the U.S.—as well as from Canada, Croatia, and Bangladesh—during the April 21-22 event presented by TCU's Neeley Entrepreneurship Center.

"Being able to do well in such a large business plan competition really says a lot about the potential of the project. This is our first competition, but it's definitely not the last."
Eric Chiang
Johns Hopkins junior

The JHU team, Treyetech—note the "eye" in the name—addressed what they identified as "pain points" during partial corneal transplant, a procedure that involves replacing a thin layer of tissue, typically 8 mm in diameter and only 15 microns thick, in the innermost layer of the front of the eye. A characteristic of the corneal tissue is that it scrolls up on itself, making it extremely difficult for surgeons to unroll during implantation.

"Imagine the size and delicacy of the tissue, and then compound that difficulty with the fact that touching the tissue is destructive—it damages the tissue and ruins the whole point of the procedure," said team leader Eric Chiang, a junior. "Once they insert the tissue, surgeons are left to tap on the eye, squirt fluid into the eye, and to try to unroll it like that. It's really just tapping, squirting, and praying."

But Treyetech's method uses a specific folding configuration and proprietary device to package corneal tissue in such a way that when the surgeon implants the tissue in the recipient's eye, it pops open in place using its own natural mechanics.

"This business has been a work in progress for over a year now," said Chiang, who attributed Treyetech's second-place finish to the pitch and presentation delivered by team members Kali Barnes, Stephanie Cai, and Conan Chen, all juniors. "Being able to do well in such a large business plan competition really says a lot about the potential of the project. This is our first competition, but it's definitely not the last."

The Treyetech team formed in JHU's Center for Bioengineering Innovation & Design, or CBID, within the undergrad design team program. CBID operates within the Johns Hopkins Department of Biomedical Engineering, which is shared by the university's School of Medicine and Whiting School of Engineering.

Also on the team are first-year students Akash Chaurasia, Allison Rosen, and Parth Vora; and junior Anshul Subramanya. Their clinical sponsor was Allen Eghrari, an assistant professor of ophthalmology at the Johns Hopkins Wilmer Eye Institute.

Treyetech received a $15,000 prize for their win, as well as in-kind prizes valued at an additional $15,000. They include three hours of marketing and branding consulting services from Ascend Concepts, six hours of IT consulting services from Comport Consulting, and two hours of legal consulting services from Winstead PC.

The Values and Ventures Business Plan Competition challenges teams to apply for-profit business models to causes that benefit the environment, the community, or specific populations.

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