In this study, we will measure CFTR function in healthy controls, healthy cystic fibrosis (CF) carriers, and CF carriers with cystic fibrosis–like illness. What is involved? A five-minute nasal brushing performed at the Johns Hopkins Outpatient Center and a review of your medical history for CF-like illnesses. You must be between 5 and 80 years old. Participants will be reimbursed for one meal. If you are interested in participating, contact Jamelia Maynard at 202-870-1395 or Jmaynar8@jhmi.edu.