The study is titled Effect of Orally Delivered Phytochemicals, Alone and in Combination, on Aging and Inflammation-Related Effects in the Skin.
Eligibility criteria:
- Fitzpatrick skin types 1 or 2: this means you are fair to light skinned, burn easily, and tan rarely
- Nonsmokers
- No recent antibiotic use
The study has the following components:
- You will be on a "cruciferous-free" diet for a month (no broccoli, cauliflower, kale, cabbage, and condiments like mustard and wasabi).
- You will be required to visit the Johns Hopkins Outpatient Center for a total of nine to 10 visits over the course of four weeks. During the visits, researchers will administer controlled UV light to multiple small areas on the buttocks. This is similar to the effects of getting a very mild sunburn. The redness of these areas will be measured daily with a chromometer and photographs will be taken. The photographs are de-identified to protect your confidentiality. Over the course of the study, 10 punch biopsies will be taken from the buttocks as well.
- Additionally, you will take a 10-day course of dietary supplements and provide two overnight 24-hour urine collections and two blood draws.
Compensation: $300 after completing all components of the study
To sign up for the study, write to Ruizhi Wang at rwang@jhmi.edu or to CTREP@jhmi.edu.
