Study seeks pregnant women planning to deliver at Johns Hopkins Hospital

Study Purpose

To determine whether fluoride supplementation during pregnancy supports the growth of beneficial oral bacteria that can protect against dental caries, as well as certain infections that can potentially cause preterm labor

Study Procedure

Participants, who must be between 10 and 20 weeks of gestation, will be randomly assigned to Group 1 (take prenatal vitamins with 3 mg fluoride added) or Group 2 (take prenatal vitamins without fluoride).

The researchers will follow up with you twice at your scheduled prenatal care visits and then at delivery for:

  • Blood
  • Urine
  • Oral & vaginal swabs (self-collected)
  • Placental samples (delivery only)
  • Umbilical cord blood (delivery only)

Compensation up to $125.

If you are interested in participating or have questions, contact Julia Clemens or Mia Feller at or 410-955-3636.

IRB number: IRB00038838
Principal investigator: Irina Burd, MD, PhD