Study seeks pregnant women receiving prenatal care at Johns Hopkins Hospital

Study Purpose
To determine whether fluoride supplementation during pregnancy supports the growth of beneficial oral bacteria that can protect against dental caries, as well as certain infections that can potentially cause preterm labor

Study Procedure Participants, who must be between 10 and 20 weeks of gestation, will be randomly assigned to Group 1 (take prenatal vitamins with 3 mg fluoride added) or Group 2 (take prenatal vitamins without fluoride).

We will follow up with you twice at your scheduled prenatal care visits and then at delivery for:

  • blood
  • urine
  • oral swab
  • vaginal swab
  • placental samples (delivery only)
  • umbilical cord blood (delivery only)

If you are interested in participating or have questions, please contact Julia Clemens at

IRB number: IRB00038838

Principal investigator: Irina Burd, MD, PhD